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How does an RNA sequence specify a functional structure, and how does the molecule find the structure with sufficient speed and accuracy to function in vivo? We are using catalytic RNAs including group I and group II introns to address these questions. DEAD-box proteins are required for essentially all RNA-mediated processes. They function by coupling ATPase activity to single-stranded RNA binding. We are studying how DEAD-box proteins use their basic properties to function as RNA chaperones.
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Universidad Técnica Federico Santa María - Campus Santiago. Universidad Técnica Federico Santa María - Campus Santiago. Licenciatura en Ciencias de la Ingeniería Informática y Bachiller en Ciencias de la Ingeniería. Primer año de Ingeniería Civil Informática. Jefe de Proyecto y Fundador.